This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.This is a multicenter randomized trial in 100 hypoxemic COPD patients comparing the physiologic and clinical benefits of utilizing lightweight ambulatory oxygen systems versus portable E-cylinder systems. The results of this investigation will provide a scientific foundation for the clinical management of hypoxemic COPD patients. It will also clarify the need for more expensive ambulatory oxygen therapy and provide incentive for technologic developments that will inevitably reduce the cost of this therapy.
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