This is a multicenter, Phase III trial of IVIG in symptomatic, HIV-infected children between 3 months and 12 years of age. Eligible children are randomized to receive monthly infusions of IVIG or placego: all children receive standard doses of oral zidovudine. Over the 100 week study period, rates of serious bacterial infections, tolerance of the drug regimens, and progression of HIV infection are assessed. Clinical, immunological, and virological outcomes will be compared.

Project Start
Project End
Budget Start
Budget End
Support Year
32
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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