The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1) is a nationwide study designed to determine whether it is possible to prevent or delay the onset of insulin-dependent diabetes mellitus, (Type 1 or IDDM). First degree relatives of people with IDDM have been screened for islet cell antibodies (ICA) (RPN # 94-01-25-06).
The aim of this study is to define the risk category for developing diabetes mellitus for those non-diabetic relatives age 3 to 45 years who have screened positive for ICA and consent to undergo further evaluation. Those individuals who screened positive will be invited to undergo """"""""staging"""""""" which consists of confirmation of ICA status., measurement of insulin autoantibodies (IAA), determination of HLA status, an intravenous glucose tolerance test (IVGTT) on two separate occasions, and an oral glucose tolerance test.

Project Start
1999-12-01
Project End
2000-11-30
Budget Start
Budget End
Support Year
39
Fiscal Year
2000
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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