Chronic infection with hepatitis C virus (HCV) is a major cause of chronic liver disease, with long term consequences including cirrhosis and hepatocellular carcinoma. Currently, the only approved treatment for HCV is Interferon Alfa (INF-alfa) alone or in combination with ribavirin. RhIL-12 has been shown to have activity against HCV infection in phase I trials. This study is designed to further assess the antiviral activity and safety of rhIL-12.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000052-39
Application #
6412613
Study Section
Special Emphasis Panel (ZRR1)
Project Start
1975-10-01
Project End
2004-11-30
Budget Start
Budget End
Support Year
39
Fiscal Year
2000
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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