INS 365 is a new molecule under study as an inhaled medication to impreve chloride and water transport and lung mucus clearance. It may also increase mucus clearance by increasing the rate at which the cilia (little hair-like fibers lining the airways) beat to push the mucus out. The purpose of this study is to evaluate the safety of a single dose of INS365 delivered by inhalation from a nebulizer to adults and children with Cystic Fibrosis. The highest dose that can be tolerated will be determined. The effect of INS365 on the amount of sputum produced will also be measured.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000052-40
Application #
6457846
Study Section
Special Emphasis Panel (ZRR1)
Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
40
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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