Phase I toxicity studies will be carried out in patients with otherwise untreatable cancer using the combination of continuous infusion vinblastine (fixed dose) and continuous infusion cyclosporine A (escalating dose).
The aim i s to determine the maximal tolerated dose of cyclosporine and determine whether concentrations of cyclosporine required to reverse vinblastine resistance are clinically achievable.

Project Start
Project End
Budget Start
Budget End
Support Year
31
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
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