This study is 1-year, randomized, double-blind, placebo-controlled trial to test the efficacy and safety of troglitazone 600 mg OD. Efficacy assessments will determine whether postprandial glucose and overall insulin sensitivity will be improved in patients with type 2 diabetes by initiating troglitazone therapy in the early stage of their diabetes. In 50% of the total number of patients randomized to study medication, beta-cell function will be assessed with a graded glucose infusion (GGI) preceded and followed by arginine stimulation and by FSIVGTT.

Project Start
1999-12-01
Project End
2001-02-28
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
39
Fiscal Year
2000
Total Cost
$32,779
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
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