The objective of this Phase I:II study is 1)to evaluate and compare the safety and dose tolerance of intermittent daily dosing regimens of oral tucaresol in patients with metastatic melanoma; 2)to explore the dose vs. immune stimulatory effect relationship of tucaresol; 3)to perform a limited investigation of the pharmacokinetics of tucaresol when administered orally in daily dosing regimens; to obtain a preliminarily assessment of the anti-tumor activity of tucaresol in patients with metastatic melanoma.

Project Start
Project End
Budget Start
Budget End
Support Year
35
Fiscal Year
1996
Total Cost
Indirect Cost
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