This category D study is designed to test the safety, pharmacokinetics, and efficacy of a liposomal amikacin preparation in stable patients with cystic fibrosis who are colonized with gram-negative bacteria. The GCRC Endoscopy Suite is used to perform serial bronchoalveolar lavage studies to determine concentration of the drug in the alveoli. The pharmacokinetic portion of the study also is well suited to the GCRC. Preliminary data on this study are not yet available for analysis.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
3M01RR000064-36S1
Application #
6419490
Study Section
Project Start
1999-12-01
Project End
2001-02-28
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
36
Fiscal Year
2001
Total Cost
$248,088
Indirect Cost
Name
University of Utah
Department
Type
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
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