Abstract

Castrated or postmenopausal women were used who received saline or doses of corticotropin releasing factors that did nor exceed 2 ug/kg every 90 mins. 11 women were studied, with only 5 completing the entire study with the 3 different dosages of CRF. The results showed that CRF had no effect on gonadotropin or prolactin secretion in the agonadol women. The most important finding was that with each successive administration there was a plateau in the secretion of ACTH but a continuous increase in cortisol secretion from the adrenal gland.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
3M01RR000068-27S1
Application #
3884217
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
27
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
University of Cincinnati
Department
Type
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221

  Publications

Feghali, Maisa; Khoury, Jane C; Shveiky, David et al. (2012) Association of vaginal delivery efforts with retinal disease in women with type I diabetes. J Matern Fetal Neonatal Med 25:27-31
Mimouni, F; Mughal, Z; Tsang, R C et al. (1995) Effect of maternal oxygen therapy on placental calcium transport in intrauterine growth retarded rats. J Am Coll Nutr 14:165-8
Samaratunga, R C; Thomas, S R; Hinnefeld, J D et al. (1995) A Monte Carlo simulation model for radiation dose to metastatic skeletal tumor from rhenium-186(Sn)-HEDP. J Nucl Med 36:336-50
Nordlund, J J; Csato, M; Babcock, G et al. (1995) Low ICAM-1 expression in the epidermis of depigmenting C57BL/6J-mivit/mivit mice: a possible cause of muted contact sensitization. Exp Dermatol 4:20-9
Green, D W; Mimouni, F; Khoury, J (1995) Decreased platelet counts in infants of diabetic mothers. Am J Perinatol 12:102-5
Luggen, M; Belhorn, L; Evans, T et al. (1995) The evolution of Raynaud's phenomenon: a longterm prospective study. J Rheumatol 22:2226-32
Cruz, M L; Bhadra, S; Subbiah, M T et al. (1994) Serum lipid peroxidation potential in infants. Arch Pediatr Adolesc Med 148:1212-5
Cruz, M L; Wong, W W; Mimouni, F et al. (1994) Effects of infant nutrition on cholesterol synthesis rates. Pediatr Res 35:135-40
Wones, R G; Deck, C C; Stadler, B et al. (1993) Lack of effect of drinking water chlorine on lipid and thyroid metabolism in healthy humans. Environ Health Perspect 99:375-81
Mimouni, F; Campaigne, B; Neylan, M et al. (1993) Bone mineralization in the first year of life in infants fed human milk, cow-milk formula, or soy-based formula. J Pediatr 122:348-54

Showing the most recent 10 out of 231 publications