Medroxyprogesterone Acetate Treatment of Adult Male Sex Offenders

Emory, Lee E.

Abstract

Medroxyprogesterone acetate (MPA) is being used clinically in the management of paraphiliac behavior. It may act centrally or through the suppression of testosterone. Ongoing assessment includes evaluation of patient's psychosocial state, reduction in fantasies leading to compulsive behavior, and biochemical changes, such as a propensity for diabetes or cholelithiasis to develop. The longitudinal outcome vs therapy is being addressed.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Center for Research Resources (NCRR)
• Type: General Clinical Research Centers Program (M01)
• Project #: 5M01RR000073-30
• Application #: 3849045
• Support Year: 30
• Fiscal Year: 1992

Institution

• Name: University of Texas Medical Br Galveston
• DUNS #: 041367053
• City: Galveston
• State: TX
• Country: United States
• Zip Code: 77555

Publications

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Hosoki, Koa; Ying, Sun; Corrigan, Christopher et al. (2015) Analysis of a Panel of 48 Cytokines in BAL Fluids Specifically Identifies IL-8 Levels as the Only Cytokine that Distinguishes Controlled Asthma from Uncontrolled Asthma, and Correlates Inversely with FEV1. PLoS One 10:e0126035

Murai, Hiroki; Okazaki, Shintaro; Hayashi, Hisako et al. (2015) Alternaria extract activates autophagy that induces IL-18 release from airway epithelial cells. Biochem Biophys Res Commun 464:969-974

Diaz, Eva C; Herndon, David N; Porter, Craig et al. (2015) Effects of pharmacological interventions on muscle protein synthesis and breakdown in recovery from burns. Burns 41:649-57

Tuvdendorj, Demidmaa; Chinkes, David L; Bahadorani, John et al. (2014) Comparison of bolus injection and constant infusion methods for measuring muscle protein fractional synthesis rate in humans. Metabolism 63:1562-7

Sallam, Hanaa S; McNearney, Terry A; Chen, Jiande D Z (2014) Acupuncture-based modalities: novel alternative approaches in the treatment of gastrointestinal dysmotility in patients with systemic sclerosis. Explore (NY) 10:44-52

Petersen, John R; Stevenson, Heather L; Kasturi, Krishna S et al. (2014) Evaluation of the aspartate aminotransferase/platelet ratio index and enhanced liver fibrosis tests to detect significant fibrosis due to chronic hepatitis C. J Clin Gastroenterol 48:370-6