Studies of therapy with the steroid metabolites, particularly 5-beta reduced products, have been pursued in patients with refractory anemia. Currently evaluation of oral absorption is being done to compare with IM treatment. Data would indicate that such metabolites can effectively enhance hematopoiesis, especially in the patients with aplastic anemia. Aplastic stem cells and thus growth response are examined in vitro.

Project Start
Project End
Budget Start
Budget End
Support Year
31
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
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