Head-down bedrest is an established ground-based model simulating a number of physiological responses experienced in microgravity, including the headward fluid shift, cardiovascular deconditioning, muscle atrophy and bone demineralization. It is hypothesized that sympathoadrenal response to bedrest will modulate peripheral vascular responses, as the result of either or both altered catecholamine levels or altered adrenergic receptor density/responsiveness, and these alterations will differ depending on fluid status.

Project Start
Project End
Budget Start
Budget End
Support Year
31
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
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