This research explores the genetic hypothesis of schizophrenia by characterizing first degree relatives of schizophrenic probands by their biological and clinical responses to two drug challenges: apomorphine and MK-212. The GH response to apomorphine and the prolactin, cortisol and hyper-thermic responses to MK-212 are compared to normal controls and unmedicated schizophrenics.

Project Start
Project End
Budget Start
Budget End
Support Year
32
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
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