Progress in determining the X-ray crystallographic structure of apolipoprotein E continues as part of the quest to better understand the interactions of lipoproteins with their receptors. These interactions regulate receptor-mediated clearance of lipoproteins and plasma lipid concentrations. Investigation of the extent of atherosclerosis in familial defective apolipoprotein B-100 patients suggests that coronary heart disease may be less prevalent in these patients.

Project Start
Project End
Budget Start
Budget End
Support Year
33
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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