Abstract

This study examines the drug interaction between 566C80, an investigational drug for the treatment of Pneumocystis carinii pneumonia, and dideoxyinosine (ddI), an approved drug for the treatment of HIV infection. 566C80 has been shown to be effective in the treatment of mild to moderate Pneumocystis carinii pneumonia. ddI is commonly given to patients with HIV infection who are also being treated with other drugs. This study will examine whether ddI will interact with 566C80 when given in combination.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000083-33
Application #
3741271
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
33
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Anderegg, Nanina; Johnson, Leigh F; Zaniewski, Elizabeth et al. (2017) All-cause mortality in HIV-positive adults starting combination antiretroviral therapy: correcting for loss to follow-up. AIDS 31 Suppl 1:S31-S40
Scherzer, Rebecca; Heymsfield, Steven B; Rimland, David et al. (2017) Association of serum albumin and aspartate transaminase with 5-year all-cause mortality in HIV/hepatitis C virus coinfection and HIV monoinfection. AIDS 31:71-79
Abid, Z; Oh, S S; Hu, D et al. (2016) Maternal age and asthma in Latino populations. Clin Exp Allergy 46:1398-1406
Rahmani, Elior; Zaitlen, Noah; Baran, Yael et al. (2016) Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies. Nat Methods 13:443-5
Morrissey, Kari M; Stocker, Sophie L; Chen, Eugene C et al. (2016) The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers. Clin Pharmacokinet 55:495-506
Wright, Patrick W; Pyakurel, Ashmit; Vaida, Florin F et al. (2016) Putamen volume and its clinical and neurological correlates in primary HIV infection. AIDS 30:1789-94
Peters, Marion G; Bacchetti, Peter; Boylan, Ross et al. (2016) Enhanced liver fibrosis marker as a noninvasive predictor of mortality in HIV/hepatitis C virus-coinfected women from a multicenter study of women with or at risk for HIV. AIDS 30:723-9
Gonzales, C A; Bacchetti, P; Khalili, M (2016) Impact of gender and menopausal status on metabolic parameters in chronic hepatitis C infection. J Viral Hepat 23:232-9
Zhi, Degui; Shendre, Aditi; Scherzer, Rebecca et al. (2015) Deep sequencing of RYR3 gene identifies rare and common variants associated with increased carotid intima-media thickness (cIMT) in HIV-infected individuals. J Hum Genet 60:63-7
Wright, Patrick W; Vaida, Florin F; Fernández, Ricardo J et al. (2015) Cerebral white matter integrity during primary HIV infection. AIDS 29:433-42

Showing the most recent 10 out of 553 publications