Patients who have HIV and DMAC, who subsequently start highly active anti-retroviral therapy and have a response noted by significant increase in CD4 count, may not need to continue to take DMAC therapy if they are asymptomatic. Before discontinuing therapy a bone marrow biopsy must be performed. The study will also look at various immune system indicators - T cells (including memory vs. naive cells and activated vs. resting), cytokine induction capacity, and lymphocyte proliferation.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000083-38
Application #
6415076
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1974-10-01
Project End
2002-11-30
Budget Start
Budget End
Support Year
38
Fiscal Year
2000
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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