This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Occurrence of nephropathy characterized by renal insufficiency in subjects with insulin-dependent diabetes mellitus(IDDM) and equivalent mentabolic control will be influenced by prior metabolic control. Risk of macrovascular disease in subjects w/IDDM can be predicted by factors measured up to 20yrs prior to the macrovascular event.
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