Malignant pleural mesothelioma is a disease with a poor prognosis. This protocol attempts to improve local control of the disease by infusing the chemotherapeutic agent directly into the pleural space, thereby increasing local drug concentration, increasing exposure of the tumor to drug, and decreasing systemic toxicities of chemotherapeutic agents. The objectives of this phase II study of intrapleural liposomal entrapped cisplatin analog (L-NDDP) are to determine the antitumor efficacy, determine time to progression and survival, toxicity, and quality of life in patients receiving this therapy.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000096-39
Application #
6412611
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1975-10-01
Project End
2003-11-30
Budget Start
Budget End
Support Year
39
Fiscal Year
2000
Total Cost
Indirect Cost
Name
New York University
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
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