Metabolic diets with fats are fed and lipoprotein and apolipoprotein levels determined. Marked interindividual variation in LDL cholesterol responsiveness to dietary changes have been noted. An attempt is being made to correlate diet responsiveness with age, sex, apo I phenotype, ad- lib lipoprotein levels, body mass index and DNA markers. Drug effects on LDL cholesterol levels are being assessed on high and low fat diets.

Project Start
Project End
Budget Start
Budget End
Support Year
28
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Rockefeller University
Department
Type
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
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