This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Anorectal malformations are uncommon congenital defects, occurring approximately 1 in 5000 live births. All patients with these malformations have lifelong problems with defecation, and, as a result, can suffer great social and physical morbidity. Although fecal incontinence scoring systems have been described in adults with anatomic fecal incontinence, there have been no studies performed to develop similar scoring systems in children with fecal incontinence due to anorectal malformations. The purpose of this study is to validate a new fecal incontinence scoring system for children with anorectal malformations. Patients who have undergone surgery for anorectal malformations will be compared to two control groups: children with eneuresis and children with no history of urinary or fecal incontinence.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000188-42
Application #
7374944
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2005-12-01
Project End
2006-11-30
Budget Start
2005-12-01
Budget End
2006-11-30
Support Year
42
Fiscal Year
2006
Total Cost
$1,551
Indirect Cost
Name
Baylor College of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
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Lanzieri, Tatiana M; Chung, Winnie; Flores, Marily et al. (2017) Hearing Loss in Children With Asymptomatic Congenital Cytomegalovirus Infection. Pediatrics 139:
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Gururangan, Sridharan; Reap, Elizabeth; Schmittling, Robert et al. (2017) Regulatory T cell subsets in patients with medulloblastoma at diagnosis and during standard irradiation and chemotherapy (PBTC N-11). Cancer Immunol Immunother 66:1589-1595

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