Abstract

This is a prospective study of aerobic exercise and weight training of frail older adults. Subjects will be recruited from the FAST study and will be randomly assigned to three interventions: low impact aerobic training (walking), weight training or health education. This study will examine the influence of exercise or weight training on glucose metabolism.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000211-31
Application #
3742203
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
31
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Tennessee Health Science Center
Department
Type
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163

  Publications

Nyenwe, Ebenezer; Owei, Ibiye; Wan, Jim et al. (2018) Parental History of Type 2 Diabetes Abrogates Ethnic Disparities in Key Glucoregulatory Indices. J Clin Endocrinol Metab 103:514-522
Messier, Stephen P; Resnik, Allison E; Beavers, Daniel P et al. (2018) Intentional Weight Loss in Overweight and Obese Patients With Knee Osteoarthritis: Is More Better? Arthritis Care Res (Hoboken) 70:1569-1575
Sanders, John T; Hastings, M Colleen; Moldoveanu, Zina et al. (2017) Serial Galactose-Deficient IgA1 Levels in Children with IgA Nephropathy and Healthy Controls. Int J Nephrol 2017:8210641
Pogacnik Murillo, Aarón Leonardo; Eckstein, Felix; Wirth, Wolfgang et al. (2017) Impact of Diet and/or Exercise Intervention on Infrapatellar Fat Pad Morphology: Secondary Analysis from the Intensive Diet and Exercise for Arthritis (IDEA) Trial. Cells Tissues Organs 203:258-266
Messier, S P; Beavers, D P; Herman, C et al. (2016) Are unilateral and bilateral knee osteoarthritis patients unique subsets of knee osteoarthritis? A biomechanical perspective. Osteoarthritis Cartilage 24:807-13
Boucher, Andrew B; Adesanya, E A Omoluyi; Owei, Ibiye et al. (2015) Dietary habits and leisure-time physical activity in relation to adiposity, dyslipidemia, and incident dysglycemia in the pathobiology of prediabetes in a biracial cohort study. Metabolism 64:1060-7
Hunter, D J; Beavers, D P; Eckstein, F et al. (2015) The Intensive Diet and Exercise for Arthritis (IDEA) trial: 18-month radiographic and MRI outcomes. Osteoarthritis Cartilage 23:1090-8
Messier, S P; Pater, M; Beavers, D P et al. (2014) Influences of alignment and obesity on knee joint loading in osteoarthritic gait. Osteoarthritis Cartilage 22:912-7
Pfeffer, Lawrence M; Li, Kui; Fleckenstein, Jaquelyn F et al. (2014) An interferon response gene signature is associated with the therapeutic response of hepatitis C patients. PLoS One 9:e104202
Look AHEAD Research Group (2014) Effect of a long-term behavioural weight loss intervention on nephropathy in overweight or obese adults with type 2 diabetes: a secondary analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol 2:801-9

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