Abstract

Significant anti-diabetic and anti-obesity effects of DHEA have been repeatedly confirmed in experimental animals, but such studies in humans are sparse. Epidemiological studies in humans, suggested a strong inverse correlation between the level of DHEA(S) and cardiovascular events in men, but not in women, and controversial results in others.""""""""

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000211-35
Application #
6306286
Study Section
Project Start
1999-12-01
Project End
2000-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
35
Fiscal Year
2000
Total Cost
$16,342
Indirect Cost

  Institution

Name
University of Tennessee Health Science Center
Department
Type
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163

  Publications

Nyenwe, Ebenezer; Owei, Ibiye; Wan, Jim et al. (2018) Parental History of Type 2 Diabetes Abrogates Ethnic Disparities in Key Glucoregulatory Indices. J Clin Endocrinol Metab 103:514-522
Messier, Stephen P; Resnik, Allison E; Beavers, Daniel P et al. (2018) Intentional Weight Loss in Overweight and Obese Patients With Knee Osteoarthritis: Is More Better? Arthritis Care Res (Hoboken) 70:1569-1575
Sanders, John T; Hastings, M Colleen; Moldoveanu, Zina et al. (2017) Serial Galactose-Deficient IgA1 Levels in Children with IgA Nephropathy and Healthy Controls. Int J Nephrol 2017:8210641
Pogacnik Murillo, Aarón Leonardo; Eckstein, Felix; Wirth, Wolfgang et al. (2017) Impact of Diet and/or Exercise Intervention on Infrapatellar Fat Pad Morphology: Secondary Analysis from the Intensive Diet and Exercise for Arthritis (IDEA) Trial. Cells Tissues Organs 203:258-266
Messier, S P; Beavers, D P; Herman, C et al. (2016) Are unilateral and bilateral knee osteoarthritis patients unique subsets of knee osteoarthritis? A biomechanical perspective. Osteoarthritis Cartilage 24:807-13
Boucher, Andrew B; Adesanya, E A Omoluyi; Owei, Ibiye et al. (2015) Dietary habits and leisure-time physical activity in relation to adiposity, dyslipidemia, and incident dysglycemia in the pathobiology of prediabetes in a biracial cohort study. Metabolism 64:1060-7
Hunter, D J; Beavers, D P; Eckstein, F et al. (2015) The Intensive Diet and Exercise for Arthritis (IDEA) trial: 18-month radiographic and MRI outcomes. Osteoarthritis Cartilage 23:1090-8
Pfeffer, Lawrence M; Li, Kui; Fleckenstein, Jaquelyn F et al. (2014) An interferon response gene signature is associated with the therapeutic response of hepatitis C patients. PLoS One 9:e104202
Look AHEAD Research Group (2014) Effect of a long-term behavioural weight loss intervention on nephropathy in overweight or obese adults with type 2 diabetes: a secondary analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol 2:801-9
Messier, Stephen P; Beavers, Daniel P; Loeser, Richard F et al. (2014) Knee joint loading in knee osteoarthritis: influence of abdominal and thigh fat. Med Sci Sports Exerc 46:1677-83

Showing the most recent 10 out of 185 publications