The study objectives include determining the efficacy of IL-2 and b-IFN + IL-2, as well as evaluating toxicity for patients with relapsed or refractory non-Hodgkin's Lymphoma. The hypothesis that there may be antiviral, antiproliferative, and immuno-modulating synergism between IL-2 and b-IFN will be uder investigation. The effect of IL-2 alone and in combination with b-IFN on in-vivo activation of NK and LAK cells will be assessed and NK and activation with tumor rresponse to therapy will be correlated.

Project Start
Project End
Budget Start
Budget End
Support Year
24
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Upstate Medical University
Department
Type
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210
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Haas, D C; Anderson Jr, G H; Streeten, D H (1985) Role of angiotensin in lethal cerebral hypoperfusion during treatment of acute hypertension. Arch Intern Med 145:1922-4