Studies are designed to elucidate the factors responsible for the gomerular hyperfiltration seen in patients with GSD-I. The natural history of progressive renal damage is assessed by using both functional studies and quantitative morphometric analysis of renal biopsies. A pilot study has been initiated to assess the efficacy of an angiotension converting enzyme inhibition on hyperfiltration and albuminuria.

Project Start
Project End
Budget Start
Budget End
Support Year
29
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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