The objectives of this investigation are 1) to compare effects of Metformin and NPH insulin on overnight rates of gluconeogenesis, glycogenolysis and hepatic glucose production in patients with T2DM and 2) to evaluate whether Metformin, given at bedtime, can be used clinically to control nocturnal hepatic glucose production in patients with T2DM.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000349-34
Application #
6420648
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
34
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Temple University
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
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