The General Clinical Research Center (GCRC) at the University of California San Diego (UCSD) supports faculty investigators throughout the Medical School in the pursuit of clinical studies judged scientifically meritorious by the GCRC Advisory Committee and approved by the UCSD Committee on Investigations Involving Human Subjects. Resources presently include 8 inpatient beds at the UCSD Medical Center with an adjacent metabolic kitchen, Clinfo Computer system, and administrative support space. A 400 square foot Core Laboratory facility is located across the street in the Clinical Teaching Facility. In addition to these facilities in the hillcrest area of San Diego, a satellite outpatient facility encompassing approximately 2000 square feet has been operational since September 1984 on the main UCSD campus in La Jolla, which is 13 miles away from the Medical Center. This facility was established to provide access to the GCRC for faculty based on the La Jolla campus and at the affiliated Veterans Administration Hospital which is located adjacent to the campus. As a result of activity at this facility, it became apparent that investigators at that locale had a definite need for inpatient investigational bed days which would be accessible in the La Jolla area. To meet these needs, a supplemental application to our GCRC grant requesting per diem bed days on the Special Diagnostic Treatment Unit (SDTU) at the Veterans Administration Hospital in La Jolla was submitted and site visited in February 1987. This application represents a competitive renewal application seeking support for the fourth 5 year cycle for our unit. Requests are made for the support deemed necessary to meet the needs of our 8 bed inpatient unit, the satellite outpatient facility on the La Jolla Campus, per diem days on the SDTU at the Veterans Administration Hospital in La Jolla, the Core Laboratory, and the Clinfo computer facility.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000827-19
Application #
3090113
Study Section
General Clinical Research Centers Committee (CLR)
Project Start
1974-03-01
Project End
1994-11-30
Budget Start
1992-12-01
Budget End
1993-11-30
Support Year
19
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Grams, Morgan E; Sang, Yingying; Ballew, Shoshana H et al. (2018) Predicting timing of clinical outcomes in patients with chronic kidney disease and severely decreased glomerular filtration rate. Kidney Int 93:1442-1451
Lavigne, Katie M; Woodward, Todd S (2018) Hallucination- and speech-specific hypercoupling in frontotemporal auditory and language networks in schizophrenia using combined task-based fMRI data: An fBIRN study. Hum Brain Mapp 39:1582-1595
Milot, Marie-Hélène; Marchal-Crespo, Laura; Beaulieu, Louis-David et al. (2018) Neural circuits activated by error amplification and haptic guidance training techniques during performance of a timing-based motor task by healthy individuals. Exp Brain Res 236:3085-3099
Hsu, Simon; Rifkin, Dena E; Criqui, Michael H et al. (2018) Relationship of femoral artery ultrasound measures of atherosclerosis with chronic kidney disease. J Vasc Surg 67:1855-1863.e1
Inker, Lesley A; Grams, Morgan E; Levey, Andrew S et al. (2018) Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium. Am J Kidney Dis :
Egnot, Natalie Suder; Barinas-Mitchell, Emma; Criqui, Michael H et al. (2018) An exploratory factor analysis of inflammatory and coagulation markers associated with femoral artery atherosclerosis in the San Diego Population Study. Thromb Res 164:9-14
Juraschek, Stephen P; Miller 3rd, Edgar R; Appel, Lawrence J (2018) Orthostatic Hypotension and Symptoms in the AASK Trial. Am J Hypertens 31:665-671
Chen, Teresa K; Appel, Lawrence J; Grams, Morgan E et al. (2017) APOL1 Risk Variants and Cardiovascular Disease: Results From the AASK (African American Study of Kidney Disease and Hypertension). Arterioscler Thromb Vasc Biol 37:1765-1769
Juraschek, Stephen P; Appel, Lawrence J; Miller 3rd, Edgar R (2017) Metoprolol Increases Uric Acid and Risk of Gout in African Americans With Chronic Kidney Disease Attributed to Hypertension. Am J Hypertens 30:871-875
Chen, Teresa K; Tin, Adrienne; Peralta, Carmen A et al. (2017) APOL1 Risk Variants, Incident Proteinuria, and Subsequent eGFR Decline in Blacks with Hypertension-Attributed CKD. Clin J Am Soc Nephrol 12:1771-1777

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