This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Compare physiological reactivity of vulnerable and nonvulnerable caregivers to experimental stressor probes. Administer both nonspecific and specific probes to assess cardiovascular reactivity. Compare vulnerable and nonvulnerable caregivers on measures of beta receptor sensitivity and density. Changes in cellular adhesion molecules that are related to platelet aggregation, with the risk of stroke, will also be measured.
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