This study addresses the efficacy and safety of interferon alpha-2b compared to interferon alpha-2b and Ribavirin in untreated hepatitis C patients. The biochemical and virological response to treatment are measured at two time points: at the end of treatment and six months posttreatment sustained response. Secondary endpoints include improve- ment in liver biopsy at posttreatment (based on the sum of Knodell scores I+II+III), time to response and time to relapse. This randomized clinical trial continues and no preliminary results are available. Future studies will focus on a long-acting form of pegylated interferon in conjunction with ribavirin.

Project Start
1998-12-01
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
25
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
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