This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of this study is to demonstrate if twice-daily subcutaneous injections of insulin glargine will produce higher serum insulin concentrations between 20-24 hours after the first injection and therefore provide better glycemic control.
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