EXCEED THE SPACE PROVIDED.The GCRC at the University of New Mexico Health Science Center is in the 26th year of continuousfunding. The geographic location of this Center permits extensive inclusion of a unique multi-ethnicresearch population. Major areas of research include:Aging: Longitudinal evaluation of an aging population with a focus on sarcopenia, but also on improvinghealth outcomes of living into the sixth through ninth decades of life.Bioengineering; Development of noninvasive spectroscopic methods to measure glucose, ethanol, andother intermediate metabolites. NASA funding has permited initial investigations on how to deliver care ata distance using rural New Mexico as a model.Endocrinology: Molecular biology of aldose-reductase modulation of the polyol pathway in patients withdiabetic neuropathy. Thyroid hormone metabolism changes induced by ingestion of naturopathicmedications.Infectious Disease: Hantavirus survivor evaluation and acute exposure prophylaxis.Metabolism: Hypocilycemiain patients with type 1 and type 2 diabetes, brain metabolism duringhypogfycemia, antioxidants and homocysteine as risk factorsfor atherosclerosis. Antipsychoticmedications and induction of insulin resistance.Nephrology: Epidemiology and genetics of end stage renal disease in Native Americans,studies ofamino acid metabolism in dialysis patients.Neonatology: Premature lung disease, intracranial hemorrhage, adrenal insufficiency in preterm infants,treatment of traumatic brain injury in chidren.Neurology: Magnetoencephalography and epilepsy, metalloproteases and multiple sclerosis, dementiaand Altzheimer's Disease interventions.Pulmonary disease: Treatment, pathophysiology, and immunology of asthma
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