The primary steps responsible for muscle insulin resistance to the pathogenesis of non-insulin dependent diabetes mellitus are unknown. This study is part of a program project the purpose of which is to distinguish between acquired and hereditary mechanisms for insulin resistance by characterizing the molecular mechanisms responsible for insulin resistance in nondiabetic subjects who have a strong genetic background for NIDDM and a high rate of progression to NIDDM. In this study, insulin resistance and NIDDM alterations in insulin-stimulated phosphorylation will be examined.

Project Start
1998-12-01
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
18
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Type
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
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