The study substance, Col-3, is a non-antibiotic tetracycline that functions as a matrix metalloprotease inhibitor. Col-3 will be administered in a dose escalating design in order to determine the maximum tolerated dose, the safety, efficacy, pharmacokinetics and pharmacodynamics of the drug.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR001346-19
Application #
6420396
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1988-12-01
Project End
2003-11-30
Budget Start
Budget End
Support Year
19
Fiscal Year
2000
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Type
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
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