This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The general aim of this study is characterization of craniofacial features in patients with craniofacial anomalies. Patients with cleft lip and palate will be compared with normal population. Growth of face is affected by surgery--a surgeon has to take into account the 'fourth dimension' (of time) while addressing three-dimensional defects in these children. Therefore, it is important to record changes in anthropometric measurements of several facial landmarks with age after repair of cleft lip and palate. Objective measurements with calipers and rulers are powerful to record such measurements, but can be time-consuming and require experts to obtain them. Newly emerging techniques in 3D digital photogrammetric techniques can help overcome these difficulties. We propose that 3D digital photogrammetric techniques will systematically and quantitatively obtain morphometric measurements in a time-efficient manner and better define facial dysmorphology in patients with craniofacial anomalies.
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