To determine peripheral blood lymphocyte and red blood cell glutathione concentration in ARDS patients at study entry and at days 1,3,7,14, and 21. These data will be correlated with clinical parameters of lung injury. To determine the effect of Procysteine therapy on the activation status of circulating poly-morphonuclear neutrophils (PMNs) by measuring hydrogen peroxide generation after ex vivo stimulation and to compare these data with determination of PMN intra-cellular glutathione concentration.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
14
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Type
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
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