1.
Specific Aim : The primary aim of the study is to compare the efficacy of Interferon and Ribavirin vs. Interferon and iron reduction therapy in clearing Hepatitis C virema. 2. Background and Preliminary studies: Hepatitis C becomes a chronic infection in over 80% of cases. Greater than 70% of patients with chronic hepatitis C treated with FDA-recommended doses of interferon fail to achieve viral clearance Further interferon courses usually obtain the same discouraging results.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR002602-16
Application #
6416158
Study Section
General Clinical Research Centers Committee (CLR)
Project Start
1985-09-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
16
Fiscal Year
2000
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Type
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Reed, Rebecca G; Greenberg, Richard N; Segerstrom, Suzanne C (2017) Cytomegalovirus serostatus, inflammation, and antibody response to influenza vaccination in older adults: The moderating effect of beta blockade. Brain Behav Immun 61:14-20
Abshire, Demetrius A; Moser, Debra K; Clasey, Jody L et al. (2017) Body Composition and Bone Mineral Density in Patients With Heart Failure. West J Nurs Res 39:582-599
Ahmed, Zuhayer; Hafez, M A; Bari, M A et al. (2016) Pattern of anti-diabetic drugs prescribed in a tertiary care hospital of Bangladesh. Int J Basic Clin Pharmacol 5:6-12
Harrison, Jordan M; Jung, Miyeon; Lennie, Terry A et al. (2016) Refusal to participate in heart failure studies: do age and gender matter? J Clin Nurs 25:983-91
Nagarajan, Radhakrishnan; Miller, Craig S; Dawson 3rd, Dolph et al. (2015) Patient-Specific Variations in Biomarkers across Gingivitis and Periodontitis. PLoS One 10:e0136792
Ebersole, Jeffrey L; Nagarajan, Radhakrishnan; Akers, David et al. (2015) Targeted salivary biomarkers for discrimination of periodontal health and disease(s). Front Cell Infect Microbiol 5:62
Ewen, Heidi H; Chahal, Jasleen K; Fenster, Emily S (2015) A portrait of resilience in caregiving. Res Gerontol Nurs 8:29-38
Alhurani, Abdullah S; Dekker, Rebecca L; Abed, Mona A et al. (2015) The association of co-morbid symptoms of depression and anxiety with all-cause mortality and cardiac rehospitalization in patients with heart failure. Psychosomatics 56:371-80
Biddle, Martha J; Lennie, Terry A; Bricker, Gregory V et al. (2015) Lycopene dietary intervention: a pilot study in patients with heart failure. J Cardiovasc Nurs 30:205-12
Janket, Sok-Ja; Baird, Alison E; Jones, Judith A et al. (2014) Number of teeth, C-reactive protein, fibrinogen and cardiovascular mortality: a 15-year follow-up study in a Finnish cohort. J Clin Periodontol 41:131-40

Showing the most recent 10 out of 232 publications