This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The auto-immune and immune medicated pathologies of Crohn's Disease (CD) highlight the similarities it shares with Acquired Immunodeficiency Syndrome (AIDS) from the human immunodeficiency virus (HIV), specifically, in the areas of pathophysiologies, anthropometric alterations, and metabolic abnormalities.
Aims : Utilize proton magnetic resonance spectroscopy imaging to measure and to compare the levels of IMCL and IHL in active CD states to iactive CD states, and both to health controls. Link the levels of IMCL and IHL to levels of inflammatory factors, adipokines, and ROS in active and inactive CD states compared to healthy controls. Determine the relationship between the levels of IMCL and IHL to resting quotient and energt expenditure using indirect calorimetry (IC) and doubly labeled water; to body composition using dual energy x-ray absorptiometry (DXA); and fasting plasma glucose levels as determined by an oral glucose tolerance test (OGTT). Model a metabolic profile of IMCL, IHL, and energy metabolism in Crohn's subjects to estimate appropriate sample size requirements for larger scale studies.
| Reed, Rebecca G; Greenberg, Richard N; Segerstrom, Suzanne C (2017) Cytomegalovirus serostatus, inflammation, and antibody response to influenza vaccination in older adults: The moderating effect of beta blockade. Brain Behav Immun 61:14-20 |
| Abshire, Demetrius A; Moser, Debra K; Clasey, Jody L et al. (2017) Body Composition and Bone Mineral Density in Patients With Heart Failure. West J Nurs Res 39:582-599 |
| Ahmed, Zuhayer; Hafez, M A; Bari, M A et al. (2016) Pattern of anti-diabetic drugs prescribed in a tertiary care hospital of Bangladesh. Int J Basic Clin Pharmacol 5:6-12 |
| Harrison, Jordan M; Jung, Miyeon; Lennie, Terry A et al. (2016) Refusal to participate in heart failure studies: do age and gender matter? J Clin Nurs 25:983-91 |
| Nagarajan, Radhakrishnan; Miller, Craig S; Dawson 3rd, Dolph et al. (2015) Patient-Specific Variations in Biomarkers across Gingivitis and Periodontitis. PLoS One 10:e0136792 |
| Ebersole, Jeffrey L; Nagarajan, Radhakrishnan; Akers, David et al. (2015) Targeted salivary biomarkers for discrimination of periodontal health and disease(s). Front Cell Infect Microbiol 5:62 |
| Ewen, Heidi H; Chahal, Jasleen K; Fenster, Emily S (2015) A portrait of resilience in caregiving. Res Gerontol Nurs 8:29-38 |
| Alhurani, Abdullah S; Dekker, Rebecca L; Abed, Mona A et al. (2015) The association of co-morbid symptoms of depression and anxiety with all-cause mortality and cardiac rehospitalization in patients with heart failure. Psychosomatics 56:371-80 |
| Biddle, Martha J; Lennie, Terry A; Bricker, Gregory V et al. (2015) Lycopene dietary intervention: a pilot study in patients with heart failure. J Cardiovasc Nurs 30:205-12 |
| Janket, Sok-Ja; Baird, Alison E; Jones, Judith A et al. (2014) Number of teeth, C-reactive protein, fibrinogen and cardiovascular mortality: a 15-year follow-up study in a Finnish cohort. J Clin Periodontol 41:131-40 |
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