While extensive progress has been made over the past decade in finding and treating patients with hypertension, it has become increasingly obvious that long term resolution of this problem will require a greater understanding of the basic mechanisms involved so that preventive measures may be taken. Recent studies have suggested that hypertension is the result of flaws in those systems which normally regulate arterial pressure. The overall objective of this proposal is to pursue studies designed to determine the mechanism(s) responsible for the altered adrenal responses to angiotensin II in essential hypertension and their pathophysiologic significance. Clinical studies will be conducted in patients with essential hypertension and parallel studies in two control groups: normotensive subjects and patients with secondary forms of hypertension.
| Scheuermaier, Karine; Münch, Mirjam; Ronda, Joseph M et al. (2018) Improved cognitive morning performance in healthy older adults following blue-enriched light exposure on the previous evening. Behav Brain Res 348:267-275 |
| Bullock, B; Murray, G; Anderson, J L et al. (2017) Constraint is associated with earlier circadian phase and morningness: Confirmation of relationships between personality and circadian phase using a constant routine protocol. Pers Individ Dif 104:69-74 |
| Klerman, Elizabeth B; Wang, Wei; Phillips, Andrew J K et al. (2017) Statistics for Sleep and Biological Rhythms Research. J Biol Rhythms 32:18-25 |
| Rachmin, Inbal; O'Meara, Caitlin C; Ricci-Blair, Elisabeth M et al. (2017) Soluble interleukin-13r?1: a circulating regulator of glucose. Am J Physiol Endocrinol Metab 313:E663-E671 |
| Buxton, Orfeu M; Pavlova, Milena K; O'Connor, Shawn P et al. (2017) Lack of change in glucose metabolism in eszopiclone-treated primary insomnia patients. Nat Sci Sleep 9:187-198 |
| Juraschek, Stephen P; Miller 3rd, Edgar R; Weaver, Connie M et al. (2017) Effects of Sodium Reduction and the DASH Diet in Relation to Baseline Blood Pressure. J Am Coll Cardiol 70:2841-2848 |
| Bray, G A; Ryan, D H; Johnson, W et al. (2017) Markers of dietary protein intake are associated with successful weight loss in the POUNDS Lost trial. Clin Obes 7:166-175 |
| Bianchi, Matt T; Phillips, Andrew J K; Wang, Wei et al. (2017) Statistics for Sleep and Biological Rhythms Research. J Biol Rhythms 32:7-17 |
| Swanson, C; Shea, S A; Wolfe, P et al. (2017) 24-hour profile of serum sclerostin and its association with bone biomarkers in men. Osteoporos Int 28:3205-3213 |
| Juraschek, Stephen P; Woodward, Mark; Sacks, Frank M et al. (2017) Time Course of Change in Blood Pressure From Sodium Reduction and the DASH Diet. Hypertension 70:923-929 |
Showing the most recent 10 out of 721 publications
