Abstract

The purpose of this study is to determine the effect of growth hormone (GH), an investigation drug, on the absorbtion of food ingested. The group of people being studied are those who have lost large segments of intestine and require home parenteral nutrition (TPN). It has been found that administering GH, and changing to a low fat diet containing fiber supplemented with the amino acid glutamine, absorbtion of food and fluid can be improved. Some people have even been removed from TPN.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR002635-15
Application #
6121341
Study Section
Project Start
Project End
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
15
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Scheuermaier, Karine; Münch, Mirjam; Ronda, Joseph M et al. (2018) Improved cognitive morning performance in healthy older adults following blue-enriched light exposure on the previous evening. Behav Brain Res 348:267-275
Swanson, C; Shea, S A; Wolfe, P et al. (2017) 24-hour profile of serum sclerostin and its association with bone biomarkers in men. Osteoporos Int 28:3205-3213
Juraschek, Stephen P; Woodward, Mark; Sacks, Frank M et al. (2017) Time Course of Change in Blood Pressure From Sodium Reduction and the DASH Diet. Hypertension 70:923-929
Hron, Bridget M; Ebbeling, Cara B; Feldman, Henry A et al. (2017) Hepatic, adipocyte, enteric and pancreatic hormones: response to dietary macronutrient composition and relationship with metabolism. Nutr Metab (Lond) 14:44
Rahman, Shadab A; St Hilaire, Melissa A; Chang, Anne-Marie et al. (2017) Circadian phase resetting by a single short-duration light exposure. JCI Insight 2:e89494
Liu, G; Liang, L; Bray, G A et al. (2017) Thyroid hormones and changes in body weight and metabolic parameters in response to weight loss diets: the POUNDS LOST trial. Int J Obes (Lond) 41:878-886
Nanba, Kazutaka; Vaidya, Anand; Williams, Gordon H et al. (2017) Age-Related Autonomous Aldosteronism. Circulation 136:347-355
Leuze, Christoph; Aswendt, Markus; Ferenczi, Emily et al. (2017) The separate effects of lipids and proteins on brain MRI contrast revealed through tissue clearing. Neuroimage 156:412-422
Gupta, Tina; Connors, Molly; Tan, Jia Wei et al. (2017) Striatin Gene Polymorphic Variants Are Associated With Salt Sensitive Blood Pressure in Normotensives and Hypertensives. Am J Hypertens 31:124-131
Tang, Olive; Miller 3rd, Edgar R; Gelber, Allan C et al. (2017) DASH diet and change in serum uric acid over time. Clin Rheumatol 36:1413-1417

Showing the most recent 10 out of 721 publications