This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to investigate biochemical factors present in the body fluids that may play a role in etiology of chronic lung disease (bronchopulmonary dysplasia), an important complication in surviving very low birth weight infants. The factors that will be evaluated include bombesin, bilirubin, aquaporins, bacterial/permeability inhibitor, complement 3a, syndecans 1 and 4, vascular endothelial growth factor, and pro-inflammatory cytokines (IL-1 beta, IL-6, IL-8, IL-11). Subjects eligible for enrollment are premature infants born at less than 29 weeks gestation.
Showing the most recent 10 out of 721 publications