This study hypothesizes that a specific opioid antagonist delivered locally to the colon can reverse the possible effects of excessive endogenous opioids and thus can be an effective treatment for constipation and other associated symptoms in constipation-predominant IBS and idiopathic constipation in the elderly.

Project Start
Project End
Budget Start
Budget End
Support Year
9
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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