Exercise Testing & Training Facility utilization only. Epidemiological studies suggest that low levels of physical activity and physical fitness are strong and independent risk factors for cardiovascular disease, cancer and all-cause mortality. Inactivity in the United States appears to be a major health problem that is of comparable magnitude to cigarette smoking, obesity, high blood pressure, and high blood cloesterol. There are over 40 million adults in the US whose sedentary habits put them at considerably increased risk of morbidity and mortality from several diseases. Exercise has been found to be a very strong predictor of successful weight management once weight loss has been achieved. No studies have compared changes in risk profiles and body composition in people treated by diet plus lifestyle activity vs. diet combined with a traditional exercise program. We hypothesize that patients who are randomized to diet-plus- lifestyle activity will maintain both weight losses and improved risk profiles significantly better than the subjects who receive the diet plus traditional exercise training because the former participants will continue to implement their increased lifestyle activity strategies into their daily schedules. The purpose of this study is to examine whether a lifestyle activity program helps patients maintain weight losses and adhere to the activity program after a supervised weight loss program. Fifty obese women will be randomly assigned to either: 1) control group, 2) diet plus lifestyle activity, or 3) diet plus traditional exercise, i.e, combined strength training and aerobic exercise in a supervised setting. We hypothesize that the women who receive the lifestyle treatment will achieve better weight maintenance and continue to pursue lifestyle activity after the supervised program is over.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR002719-13A1
Application #
6281968
Study Section
Project Start
1998-07-10
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
13
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Unick, Jessica L; Gaussoin, Sarah A; Hill, James O et al. (2017) Objectively Assessed Physical Activity and Weight Loss Maintenance among Individuals Enrolled in a Lifestyle Intervention. Obesity (Silver Spring) 25:1903-1909
Li, Tianjing; Wieland, L Susan; Oh, Esther et al. (2017) Design considerations of a randomized controlled trial of sedation level during hip fracture repair surgery: a strategy to reduce the incidence of postoperative delirium in elderly patients. Clin Trials 14:299-307
Sammut, Amanda; Shea, Steven; Blumenthal, Roger S et al. (2017) Albuminuria in Rheumatoid Arthritis: Associations With Rheumatoid Arthritis Characteristics and Subclinical Atherosclerosis. Arthritis Care Res (Hoboken) 69:1799-1808
Baker, Joshua F; Giles, Jon T; Weber, David et al. (2017) Assessment of muscle mass relative to fat mass and associations with physical functioning in rheumatoid arthritis. Rheumatology (Oxford) 56:981-988
Johnson, Karen C; Bray, George A; Cheskin, Lawrence J et al. (2017) The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial. J Bone Miner Res 32:2278-2287
Chao, Ariana M; Wadden, Thomas A; Gorin, Amy A et al. (2017) Binge Eating and Weight Loss Outcomes in Individuals with Type 2 Diabetes: 4-Year Results from the Look AHEAD Study. Obesity (Silver Spring) 25:1830-1837
Park, H-W; Tse, S; Yang, W et al. (2017) A genetic factor associated with low final bone mineral density in children after a long-term glucocorticoids treatment. Pharmacogenomics J 17:180-185
McGeachie, Michael J; Yates, Katherine P; Zhou, Xiaobo et al. (2016) Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma. Am J Respir Crit Care Med 194:1465-1474
Marquez, Becky; Anderson, Andrea; Wing, Rena R et al. (2016) The relationship of social support with treatment adherence and weight loss in Latinos with type 2 diabetes. Obesity (Silver Spring) 24:568-75
Kavouspour, Chitra; Wang, NaeYuh; Mears, Simon C et al. (2016) Surgical procedure and postoperative delirium in geriatric hip fracture patients. Eur J Anaesthesiol 33:230-1

Showing the most recent 10 out of 406 publications