There is a revised renewal request for the Tulane-Louisiana State University-Charity Hospital GCRC. The initial grant was awarded from 1/14/90 through 11/13/93 during which time the research facility was constructed and research activities were initiated and rapidly expanded. A second renewal request was funded from 12/1/93 to 11/30/98. During this time the Center continued to grow rapidly with numbers of inpatients and particularly outpatients, exceeding those initially projected. The current application is for our second five year renewal.
Our specific aims are to: (1) provide a well-staffed and considerably expanded facility that will allow quality inpatient and outpatient care for adult and pediatric patients who are subjects of research projects within the framework of the overall Tulane-LSU-Charity Hospital Medical Complex; (2) to ensure that these projects continue to be performed under controlled conditions and with scientific rigor; (3) to continue support of our Core Laboratory which processes specimens and develops state-of-the-art assays for many of the researchers who use the GCRC resulting in increased scientific productivity and reduced costs; (4) to provide other postgraduate students, medical students, fellows, nurses, and certain paramedical personnel within the Tulane-LSU-Charity Hospital MEDICAL Complex; (5) to have the facility serve as a role model for leveraging new grants and improving quality of patient care by applying the advances resulting from these clinical research projects to disease diagnosis and therapy. Our program will continue to stress the following. (1) a strong interdisciplinary effort by both medical schools; (2) a strong commitment from the Deans of both institutions; (3) emphasis on quality research projects; (4) maintaining our track record of demonstrated interaction and productivity working relationships between Tulane, LSU, and Charity Hospital.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR005096-10A1
Application #
2885217
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Program Officer
Beitins, Inese Z
Project Start
1990-01-14
Project End
2001-11-30
Budget Start
1999-07-19
Budget End
1999-11-30
Support Year
10
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Tulane University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New Orleans
State
LA
Country
United States
Zip Code
70118
Allegrezza, Michael J; Rutkowski, Melanie R; Stephen, Tom L et al. (2016) Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis. Cancer Res 76:6253-6265
Drerup, Justin M; Liu, Yang; Padron, Alvaro S et al. (2015) Immunotherapy for ovarian cancer. Curr Treat Options Oncol 16:317
Chyun, Deborah A; Wackers, Frans J Th; Inzucchi, Silvio E et al. (2015) Autonomic dysfunction independently predicts poor cardiovascular outcomes in asymptomatic individuals with type 2 diabetes in the DIAD study. SAGE Open Med 3:2050312114568476
Rahman, Mahboob; Xie, Dawei; Feldman, Harold I et al. (2014) Association between chronic kidney disease progression and cardiovascular disease: results from the CRIC Study. Am J Nephrol 40:399-407
Kempen, John H; Sugar, Elizabeth A; Varma, Rohit et al. (2014) Risk of cataract among subjects with acquired immune deficiency syndrome free of ocular opportunistic infections. Ophthalmology 121:2317-24
Ricardo, Ana C; Yang, Wei; Lora, Claudia M et al. (2014) Limited health literacy is associated with low glomerular filtration in the Chronic Renal Insufficiency Cohort (CRIC) study. Clin Nephrol 81:30-7
Kozak, Igor; Vaidya, Vijay; Van Natta, Mark L et al. (2014) The prevalence and incidence of epiretinal membranes in eyes with inactive extramacular CMV retinitis. Invest Ophthalmol Vis Sci 55:4304-12
Wing, Maria R; Devaney, Joseph M; Joffe, Marshall M et al. (2014) DNA methylation profile associated with rapid decline in kidney function: findings from the CRIC study. Nephrol Dial Transplant 29:864-72
Mariani, Laura H; White, Matthew T; Shults, Justine et al. (2014) Increasing use of vitamin D supplementation in the chronic renal insufficiency cohort study. J Ren Nutr 24:186-93
Wing, Maria R; Yang, Wei; Teal, Valerie et al. (2014) Race modifies the association between adiposity and inflammation in patients with chronic kidney disease: findings from the chronic renal insufficiency cohort study. Obesity (Silver Spring) 22:1359-66

Showing the most recent 10 out of 211 publications