This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Since 1994, worldwide HIV/AIDS-related inpatient admissions and the average length of stay for these admissions have both been in steady decline. Furthermore, since the 1996 advent of HAART (highly active antiretroviral therapy), these downward trends have accelerated, with total bed-days and patient expenditures also decreasing. However, MCLNO has continued to have a high rate of HIV/AIDS related admissions and routinely operates at near capacity. Conventionally accepted risk factors for HIV/AIDS-related admissions include drug use, alcohol use, psychiatric disease, non-adherence to medications and/or outpatient visits, CD4 count, HIV viral load, and history of OIs and prophylaxis for OIs. The purpose of this study is to elucidate the role of each of these factors in determining inpatient admissions at MCLNO and therefore lead to enhanced outpatient services that will decrease the need for less convenient and more expensive inpatient services.
The aims are to: 1) perform a cross-sectional case-control study with multivariate logistic regression analysis of factors associated with hospital admissions related to HIV/AIDS. Cases will consist of hospitalized HIV/AIDS patients and controls will be identified from the outpatient HIV clinic. Cases will be matched by CD4, age and gender. Factors analyzed will include substance abuse, psychiatric disease, nonadherence, poor social support, patient-physician relationship, and opportunistic coinfections; 2) to determine whether patients perceive that a dedicated HIV/AIDS hospital ward provides higher patient satisfaction than a non-specialized ward.
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