This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This research study will compare the treatment of three different asthma medications in asthma patients whose asthma is well controlled when they take fluticasone, and inhaled corticosteroid. The treatments are fluticasone (for example, Flovent), montelukast (an anti-leukotriene drug; for Singulair), and salmeterol (a long-acting beta agonist; for example Serevent). Fluticasone, montelukast and salmeterol are all approved for the treatment of asthma. We are looking at whether the three treatments are equally effective for reducing the number and the severity of asthma attacks in people with mild to moderately severe asthma. This study is being conducted at several clinical centers across the United States. Approximately 495 subjects will participate in this research study. Approximately 20 patients will be participating at the LSU site.
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