Abstract

Children with renal failure generally develop renal osteodystrophy and severe growth failure. Therefore, this study as part of a multicenter, double-blind study (18 institutions) will assess the effects of 1,25-dihydroxyvitamin-D3 on growth, skeletal density, nutritional status, and biochemical parameters of renal failure. There will be an initial 6-month control period, and then patients will be randomized to receive 1,25-dihydroxyvitamin-D3 or dihydrotachysterol.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR006021-02
Application #
3871897
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Thompson, S J; Auslander, W F; White, N H (2001) Comparison of single-mother and two-parent families on metabolic control of children with diabetes. Diabetes Care 24:234-8
Thompson, S J; Auslander, W F; White, N H (2001) Influence of family structure on health among youths with diabetes. Health Soc Work 26:7-14
Arfken, C L; Reno, P L; Santiago, J V et al. (1998) Development of proliferative diabetic retinopathy in African-Americans and whites with type 1 diabetes. Diabetes Care 21:792-5
Auslander, W F; Thompson, S; Dreitzer, D et al. (1997) Disparity in glycemic control and adherence between African-American and Caucasian youths with diabetes. Family and community contexts. Diabetes Care 20:1569-75
Reno, P L; Arfken, C L; Heins, J M et al. (1997) Factors that influence the decision to receive treatment for proliferative diabetic retinopathy. Diabetes Educ 23:653-5
Auslander, W F; Thompson, S J; Dreitzer, D et al. (1997) Mothers' satisfaction with medical care: perceptions of racism, family stress, and medical outcomes in children with diabetes. Health Soc Work 22:190-9
Arfken, C L; Schmidt, L E; McGill, J B et al. (1996) Major decrements in glycated hemoglobin levels between 1978 and 1989 in patients with insulin-dependent diabetes mellitus. J Diabetes Complications 10:12-7
Bonilla-Felix, M; Villegas-Medina, O; Vehaskari, V M (1994) Renal acidification in children with idiopathic hypercalciuria. J Pediatr 124:529-34
Arfken, C L; Salicrup, A E; Meuer, S M et al. (1994) Retinopathy in African Americans and whites with insulin-dependent diabetes mellitus. Arch Intern Med 154:2597-602
Noel, G J; Katz, S L; Edelson, P J (1991) The role of C3 in mediating binding and ingestion of group B streptococcus serotype III by murine macrophages. Pediatr Res 30:118-23