This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this project is to evaluate and compare rates of adherence to medication regimes for HIV patients between self-administered antiretroviral therapy and directly-observed therapy (DOT) in incarcerated patients. Secondary aims include determining if electronic monitoring with directed cue-dosed counseling and/or DOT improves adherence rates of subsequent self-administered therapy, to correlate improvements in adherence with clinical response to HAART, and to characterize patients who may maximally benefit from each dosing strategy
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