This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Otoacoustic emissions (OAEs) are sounds generated by the inner ear and their properties have been used to assess inner ear function. There are a number of ways of eliciting and measuring OAEs, e.g., click-evoked OAEs or distortion product OAEs. Both of these techniques are currently in use clinically, however, it is recognized that both have shortcomings (i.e., poor frequency specificity in the case of click-evoked and as yet indeterminant site of DPOAE generation thus unclear correlation with site of cochlear pathology in the case of DPOAEs). Stimulus frequency otoacoustic emissions (SFOAEs) offer the most frequency specific method of assessing function along the cochlear partition. Up to now measurement of SFOAEs has been too time consuming to allow use in clinical applications. We have developed a rapid method for recording stimulus frequency otoacoustic emissions (SFOAEs). Here we propose to develop this technique into a useful clinical tool with potential to replace CEOAES and DPOAEs, and obtain normative data and preliminary results from hearing impaired listeners.
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