This study is a component of a multi-center, double-blind, parallel clinical safety study. It will test the tolerances and efficacy of the thromboxane receptor antagonist, Ifetroban. Evidence clearly suggests that the production of thromboxane may play a role in the baso-spastic element of claudication. Using a standardized exercise protocol over twelve weeks, Ifetroban's effects will be evaluated at three different doses. The expected outcome is improved claudication time.

Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
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