This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Children with JRA are at risk for low bone mass and fracture in early adulthood. The present project compares a Behavior Intervention Program (BI) to an enhanced standard of care condition (ESC) for increasing dietary calcium intake and bone mass in children with JRA. The program evaluates dietary calcium intake pre to post intervention (approximately 8 weeks later) and at 6 month intervals over 2 years. Bone mass is also examined at baseline and at 6 month intervals for 2 years post treatment. It is hypothesized that children with JRA receiving the BI will have a significantly greater dietary calcium intake per day than children with JRA receiving ESC pre to post treatment (8 weeks). It is also hypothesized that the increased calcium intake of the BI group will be maintained across 24 months post treatment and that the calcium intake of the BI group will be significantly greater than the ESC group. Finally, it is hypothesized that the BI condition will result in a significantly greater increase in bone mass than the ESC.
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